Clinical Trials on Maxillary Expansion in Germany - Clinical Trials Registry (2025)

• Dr. August Wolff GmbH & Co. KG Arzneimittel

  Completed

  Assessment of Safety, Tolerability, Systemic Exposure and Efficacy of GPB Cream in Adolescents With Severe Primary Hyperhidrosis

  Primary Axillary Hyperhidrosis

  Germany

• Dr. August Wolff GmbH & Co. KG Arzneimittel

  Completed

  Assessment of Efficacy and Safety of Topical Administration of 1% Glycopyrronium Bromide (GPB) in Patients With Primary Axillary Hyperhidrosis and the Assessment of Long-term Efficacy and Safety of Topical Administration of 1% GPB Cream in Patients With Primary Axillary Hyperhidrosis.

  Primary Axillary Hyperhidrosis

  Germany

• Ulthera, Inc

  Completed

  Evaluation of the Ulthera System for Treating Axillary Hyperhidrosis (ULT-218)

  Axillary Hyperhidrosis

  Germany

• Dr. August Wolff GmbH & Co. KG Arzneimittel

  FGK Clinical Research GmbH; Nuvisan GmbH; Charles River Biopharmaceutical Services...

  Completed

  Investigation of Ascending Concentrations of Glycopyrronium Bromide (GPB) in a Topical Formulation in Subjects With Axillary Hyperhidrosis

  Primary Axillary Hyperhidrosis

  Germany

• Göteborg University

  University of Sheffield; Region Örebro County

  Recruiting

  The Effectiveness of Early Intervention to Correct the Position of PDC:s (PDC)

  Randomized Clinical Trial | Palatal Expansion Technique | Ectopic Tooth Eruption

  Sweden, Germany, United Kingdom

• Fidia Farmaceutici s.p.a.

  Completed

  ONCOFID-P-B in the Intravescical Therapy of Patients With Non-muscle Invasive Cancer of the Bladder.

  Non-Invasive Papillary Carcinoma of Bladder

  Spain, Germany, Italy

• Universitätsklinikum Hamburg-Eppendorf

  Recruiting

  See Also

  Comparison of palatal expanders and their efficacy: a narrative reviewEvaluation of the stiffness characteristics of rapid palatal expander screwsBone First MARPEs with Insertion Guides

  KTP Laser vs Pulsed Dye Laser for Port-Wine Stains

  Port-Wine Stain

  Germany

• Baxter Healthcare Corporation

  Completed

  Efficacy and Safety of Fibrin Sealant Vapor Heated Solvent/Detergent Treated (FS VH S/D) for Reduction of Lymphatic Leakage by Sealing Axillary Lymph Node Dissection Sites

  Breast Cancer | Lumpectomy | Mastectomy Plus Axillary Lymph Node Dissection | Lymphatic Leakage

  Germany, Austria, France, Italy

• Dentsply Sirona Implants

  Completed

  Multicenter Study Comparing OsseoSpeed TX With OsseoSpeed EV.

  Partial Edentulism in the Maxilla or in the Mandible

  United States, Belgium, Germany, Italy

• Novartis Pharmaceuticals

  Terminated

  A Phase I/Ib Study of NIZ985 Alone and in Combination With Spartalizumab

  In Escalation: All Patients With Solid Tumors and Lymphoma | In Expansion: Melanoma, Non-small Cell Lung Cancer

  United States, Italy, Taiwan, Belgium, Spain, Germany, Japan

• Pfizer

  Completed

  A Multicenter, Randomized, Double-Blind, Double-Dummy Trial of Azithromycin SR Compared With Levofloxacin for the Treatment of Sinus Infections in Adults

  Maxillary Sinusitis

  United States, Costa Rica, Chile, India, Slovakia, Argentina, Czech Republic, Estonia, Germany, Lithuania, Mexico, Poland, Russian Federation

• Head and Neck Cancer International Group

  Completed

  Ascertaining the Radiologic Prognostic Importance of Extranodal Extension on Imaging (iENE) in Head and Neck Cancer (EPIC-iENE DATA)

  Head and Neck Squamous Cell Carcinoma | Extranodal Extension | Human Papilloma Virus Related Carcinoma

  Switzerland, United Kingdom, United States, Germany, Australia, France, Spain, Denmark

• Eli Lilly and Company

  Loxo Oncology, Inc.

  Active, not recruiting

  A Study of Oral LOXO-292 (Selpercatinib) in Pediatric Participants With Advanced Solid or Primary Central Nervous System (CNS) Tumors (LIBRETTO-121)

  Soft Tissue Sarcoma | Medullary Thyroid Cancer | Papillary Thyroid Cancer | Infantile Fibrosarcoma | Infantile Myofibromatosis

  United States, Canada, Australia, Japan, France, Denmark, United Kingdom, Korea, Republic of, Spain, Italy, Germany

• Eli Lilly and Company

  Eli Lilly and Company

  Approved for marketing

  Expanded Access for the Treatment of Cancers With Rearranged During Transfection (RET) Activation

  Breast Cancer | Pancreatic Cancer | Non Small Cell Lung Cancer | Colon Cancer | Medullary Thyroid Cancer | Papillary Thyroid Cancer | Other Solid Tumors With Evidence of Activating RET Alteration

  United States, Poland, Australia, Japan, Germany, France, Spain, Israel, Italy, Switzerland, Hong Kong, New Zealand, Singapore

• Novartis Pharmaceuticals

  Completed

  RAPTOR: RAD001 as Monotherapy in the Treatment of Advanced Papillary Renal Cell Tumors Program in Europe (MACS0460)

  Adenocarcinoma | Carcinoma | Renal Cell | Non Clear Cell Renal Carcinoma | Papillary Cell Renal Carcinoma

  France, Italy, Belgium, Germany, Spain, Poland

• Pierre Fabre Dermatology

  Completed

  Study to Demonstrate the Efficacy and Safety of Propranolol Oral Solution in Infants With Proliferating Infantile Hemangiomas Requiring Systemic Therapy

  Infantile Hemangioma

  Germany, United States, France, Spain, Peru, Australia, Lithuania, Italy, Canada, Czech Republic, Hungary, Mexico, New Zealand, Poland, Romania, Russian Federation

• Hoffmann-La Roche

  Completed

  Phase 1/2 Study of the Highly-selective RET Inhibitor, Pralsetinib (BLU-667), in Participants With Thyroid Cancer, Non-Small Cell Lung Cancer, and Other Advanced Solid Tumors (ARROW)

  Neoplasms | Neoplasms by Histologic Type | Lung Diseases | Neoplasms by Site | Adenocarcinoma | Carcinoma | Neoplasms, Glandular and Epithelial | Endocrine System Diseases | Gastrointestinal Neoplasms | Neoplasms, Germ Cell and Embryonal | Head and Neck Neoplasms | Carcinoma, Non-Small-Cell Lung | Respiratory Tract... and other conditions

  France, Spain, United States, Korea, Republic of, United Kingdom, Taiwan, China, Belgium, Singapore, Netherlands, Germany, Italy, Hong Kong

• Fred Hutchinson Cancer Center

  National Cancer Institute (NCI); National Heart, Lung, and Blood Institute...

  Completed

  Total-Body Irradiation and Fludarabine Phosphate Followed by Donor Peripheral Blood Stem Cell Transplant in Treating Patients With Hematologic Malignancies or Kidney Cancer

  Clear Cell Renal Cell Carcinoma | Chronic Myelomonocytic Leukemia | Previously Treated Myelodysplastic Syndrome | Recurrent Adult Acute Myeloid Leukemia | Recurrent Adult Lymphoblastic Lymphoma | Untreated Adult Acute Myeloid Leukemia | Adult Acute Myeloid Leukemia in Remission | Childhood Acute... and other conditions

  United States, Germany, Italy

• European Organisation for Research and Treatment...

  Pfizer

  Completed

  CREATE: Cross-tumoral Phase 2 With Crizotinib (CREATE)

  Locally Advanced and/or Metastatic Anaplastic Large Cell Lymphoma | Locally Advanced and/or Metastatic Inflammatory Myofibroblastic Tumor | Locally Advanced and/or Metastatic Papillary Renal Cell Carcinoma Type 1 | Locally Advanced and/or Metastatic Alveolar Soft Part Sarcoma | Locally Advanced... and other conditions

  France, Belgium, Netherlands, Germany, United Kingdom, Italy, Norway, Poland, Slovakia, Slovenia

• AstraZeneca

  Active, not recruiting

  Savolitinib Plus Durvalumab Versus Sunitinib and Durvalumab Monotherapy in MET-Driven, Unresectable and Locally Advanced or Metastatic PRCC (SAMETA)

  Papillary Renal Cell Carcinoma

  Canada, Italy, Spain, United Kingdom, Czechia, Poland, Argentina, United States, Germany, Korea, Republic of, Brazil, Mexico, China, Taiwan, Hong Kong, Australia, Turkey, Israel, Netherlands, France, Romania, Singapore, India, Chile, Uk...

• Fred Hutchinson Cancer Center

  National Cancer Institute (NCI); National Heart, Lung, and Blood Institute...

  Completed

  Fludarabine Phosphate, Low-Dose Total Body Irradiation, and Donor Stem Cell Transplant in Treating Patients With Hematologic Malignancies or Kidney Cancer

  Clear Cell Renal Cell Carcinoma | Recurrent Adult Acute Myeloid Leukemia | Extranodal Marginal Zone B-cell Lymphoma of Mucosa-associated Lymphoid Tissue | Nodal Marginal Zone B-cell Lymphoma | Recurrent Adult Diffuse Small Cleaved Cell Lymphoma | Recurrent Grade 1 Follicular Lymphoma | Recurrent... and other conditions

  United States, Germany

• Hoffmann-La Roche

  Active, not recruiting

  Basket Study of Entrectinib (RXDX-101) for the Treatment of Patients With Solid Tumors Harboring NTRK 1/2/3 (Trk A/B/C), ROS1, or ALK Gene Rearrangements (Fusions) (STARTRK-2)

  Melanoma | Renal Cell Carcinoma | Adult Solid Tumor | Breast Cancer | Head and Neck Neoplasms | Colorectal Cancer | Pancreatic Cancer | Ovarian Cancer | Non-Small Cell Lung Cancer | Neuroendocrine Tumors | Lymphoma, Large-Cell, Anaplastic | Cholangiocarcinoma | Papillary Thyroid Cancer | Sarcomas | Salivary Gland Cancers and other conditions

  United States, France, Spain, China, Australia, United Kingdom, Hong Kong, Belgium, Germany, Taiwan, Japan, Korea, Republic of, Singapore, Italy, Poland, Netherlands

• European Organisation for Research and Treatment...

  Recruiting

  Observational Study for Assessing Treatment and Outcome of Patients With Primary Brain Tumours Using cIMPACT-NOW and 2021 WHO Classification

  Glioma | Ependymoma | Hemangiopericytoma | Diffuse Midline Glioma, H3 K27M-Mutant | Germ Cell Tumor | Embryonal Tumor | Hemangioblastoma | Glioneuronal Tumor | Choroid Plexus Tumor | Pineal Tumors | Tumor of the Sellar Region | Pineal Tumor | Melanocytic Tumor of CNS

  France, Netherlands, Spain, Italy, Belgium, Germany, Norway, Switzerland, United Kingdom, Austria, Greece, Portugal

• Novartis Pharmaceuticals

  Completed

  Study of Efficacy and Safety of Dabrafenib in Combination With Trametinib in Pediatric Patients With BRAF V600 Mutation Positive LGG or Relapsed or Refractory HGG Tumors

  Glioblastoma | Astrocytoma | Anaplastic Astrocytoma | Anaplastic Ganglioglioma | Anaplastic Pleomorphic Xanthoastrocytoma | Ganglioglioma | Pleomorphic Xanthoastrocytoma | Diffuse Astrocytoma | Anaplastic Oligodendroglioma | Pilocytic Astrocytoma | Gangliocytoma | Central Neurocytoma | Oligodendroglioma, Childhood and other conditions

  United States, Italy, Japan, Germany, Spain, France, Canada, Australia, Brazil, Israel, Russian Federation, Argentina, United Kingdom, Finland, Belgium, Denmark, Czechia, Sweden, Switzerland, Netherlands

• Fred Hutchinson Cancer Center

  National Cancer Institute (NCI); National Heart, Lung, and Blood Institute...

  Completed

  Mycophenolate Mofetil and Cyclosporine in Reducing Graft-Versus-Host Disease in Patients With Hematologic Malignancies or Metastatic Kidney Cancer Undergoing Donor Stem Cell Transplant

  Clear Cell Renal Cell Carcinoma | Chronic Myelomonocytic Leukemia | Recurrent Adult Acute Myeloid Leukemia | Juvenile Myelomonocytic Leukemia | Extranodal Marginal Zone B-cell Lymphoma of Mucosa-associated Lymphoid Tissue | Nodal Marginal Zone B-cell Lymphoma | Recurrent Adult Burkitt Lymphoma | Recurrent... and other conditions

  United States, Germany, Italy

• Novartis Pharmaceuticals

  Active, not recruiting

  Pediatric Long-Term Follow-up and Rollover Study

  Glioblastoma | Astrocytoma | Anaplastic Astrocytoma | Neurofibromatosis Type 1 | Anaplastic Ganglioglioma | Anaplastic Pleomorphic Xanthoastrocytoma | Ganglioglioma | Pleomorphic Xanthoastrocytoma | Diffuse Astrocytoma | Anaplastic Oligodendroglioma | Pilocytic Astrocytoma | Gangliocytoma | Central Neurocytoma | Oligodendroglioma... and other conditions

  United States, Italy, Japan, Germany, France, Belgium, Canada, Australia, Brazil, Czechia, Russian Federation, Argentina, Denmark, United Kingdom, Spain, Finland, Sweden, Netherlands, Israel

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